Synergistic interaction between silver nanoparticles and membrane-permeabilizing antimicrobial peptides.

نویسندگان

  • Serge Ruden
  • Kai Hilpert
  • Marina Berditsch
  • Parvesh Wadhwani
  • Anne S Ulrich
چکیده

Silver nanoparticles, as well as antimicrobial peptides (AMPs), can be used to fight infectious diseases. Since AMPs are known to permeabilize bacterial membranes and might therefore help silver nanoparticles to access internal target sites, we investigated their combined activities and showed synergistic effects between polymyxin B and silver nanoparticles for gram-negative bacteria.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 53 8  شماره 

صفحات  -

تاریخ انتشار 2009